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Structure of PDB 5xxu Chain b Binding Site BS01

Receptor Information >5xxu Chain b (length=79) Species: 5811 (Toxoplasma gondii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] EIDLLHPDPKVEASKHKLKRLIPNPNSFFMDVKCPGCLQITTVFSHAQTV VLCGSCNIMLCQPTGGKCKLTEGCSFRKK

Ligand information >5xxu Chain 2 (length=1619) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aaccugguugauccugccaguagucauaugcuugucuuaaagauuaagcc augcaugucuaaguauaagcuuuuauacggcuaaacugcgaauggcucau uaaaacaguuauaguuuauuugauggucuacauggauaaccgugguaauu cuauggcuaauaccugcgcacaguguuuauuagauacagaaccaagguga uucauaguaaccgaacggaucgcgcugcgacggaucauucaaguuucuga ccuaucagcuuucgacgguacuguaauggacuaccguggcagugacgggu aacggggaauuaggguucgauuccggagagggagccugagaaacggcuac cacaucuaaggaaggcagcaggcgcgcaaauuacccaauccugauucagg gagguagugacaagaaauaacaaccuggagugauuggaugauaggaaucc aaaccccuuucagaguaacaauuggagggcaagucuggugccagcagccg cgguaauuccagcuccaauagcguauauuaaaguuguugcaguuaaaaag cucguaguuggauuucugcuggaaggccaauucuagcauccuucuggacu uuuacuuugagaaaauuagaguguuucaagcaggcuugucgccuugaaua cucagcauggaauaauaagauuucggcccuauuuugguuucuaggacuga aguaaugauuaauagggacgguugggggcauucguauuuaacugucagag gugaaauucuuagauuuguuaaagacgaacuacugcgaaagcauuugcca aagauguuuucauuaaucaagaacgaaaguuaggggcucgaagacgauca gauaccgucguagucuuaaccauaaacuaugccgacuagagauaggaaaa cgucaugacuucuccugcaccuuaugagaaaccaaagucuuuggguucug gggggaguauggucgcaaggcugaaacuuaaaggaauugacggaagggca ccaccaggcguggagccugcggcuuaauuugacucaacacggggaaacuc accagguccagacauaggaauugacagauugauagcucuuucuugauucu augggugguggugcauggccguucuuaguugguggagugauuugucuggu uaauuccguuaacgaacgagaccuuaaccugcuaaauaggaucaggaacu ucguguucuuguaucacuucuuagagggacuuugcgugucuaacgcaagg aaguuugaggcaauaacaggucugugaugcccuuagauguucugggcugc acgcgcgcuacacugaugcauccaacgaguccuuggccgauaggucuagg uaaucuugugaguaugcaucgugauggggauagauuauugcaauuauuaa ucuucaacgaggaaugccuaguaggcgcaagucagcacguugcgccgauu acgucccugcccuuuguacacaccgcccgucgcuccuaccgauugagugu uccggugaauuauucggaccguuuuguggcccgaaaugggaaguuuugug aaccuuaacacuuagaggaaggagaagucguaacaagguuuccguaggug aaccugcggaaggaucauu ...<<<<<.{.[[[[>>>>><<<..<<<<<<...<<<<..<......<<< .<<<..<<....<<....<<<.......>>>...>>.>>......<<..< .....<<<..<<..<<....<<<<.........<.....<<<<<<..... >>>>>>......>.........<<..<<<<<<.......(((((...... ....>>>>>>....>>...<<<<...>>>>...>>>>...>>>>..>>>. <<<....<<<....<<<<<<...........>>>>>>>>>......>>>. ..<<<.<<<<....>>>>....>>>>>>.<<.<<<..........>>>.> >.<.<<....>>.>...>>>>>>.........<<<....<<<.....>>> ..>>>..>...>>>>.....<<<.<....>...>>>.....<.<<<.... .......>>>.>.........<<<<<((....<.<<<<.....<<..))> >.......>>>>>>>>>>..>>>>>>.>>>.........<<<[[.....< .<<...<<<.<<.....<<<<<<<......>>>>>>>.....<...>... .<<<<<.<<.......<<...<.......>..<<<.....>>>.....>> .....>>.>>..>>>.....<<<<<<.<<<....)))))...>>>.>>>> >>......>>....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<< ......>>>......>.>>>>>.>.>>.......<<....>>...>>>>. ..>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.<.. ...>.>>>>...>>>>>>>>..........<<<.<<.<<.<.<<<<<.<< .<<<..>>>>>.>>>>>..>>>...<...]].>...>>.....>>>.>>> .<<<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<< ..<<.<<<<<<..<<<.<<<<<<......<<........>>......... .<<<<<.<....<<<<<......<..<<........>>..>.......>> >>>...<<.<<<..<<.<<<<<<....<<<.<<<<......>>...<<<. .....>>>...>>.>>>....<<<<<.<<..<<<<..<<....<<<<<<. ....>>>>>>......>>..>>>>.>>....<<<<<<.....>>>>>.>. .....>>>>>....>>>.>>>.....>>>>>>>.....>.>>>>>...>> .>>>>.>>>.....<<<<<<<......<<.<<<.<<<<....>>>>.>>> ....>>.......>>>>>>>...........<<<<<<..........>>> >>>..........>>>>>>....<<<<<<<.........>>>>>>>.... ..>>...>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<<<<< <..<<<..<<.<..<...<<<<<<<<.....>>>>>>>>...>..>.>>. .>>>..>>>>>>>...>>.>>>>>..>.>>...>.....<<<<<<<<<<. .>>>>>>>>>>........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 5xxu Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Resolution 3.35 Å Binding residue (original residue number in PDB) S15 H17 K18 L19 K20 P26 S28 H47 Q49 T65 G66 G67 K68 K70 Binding residue (residue number reindexed from 1) S14 H16 K17 L18 K19 P25 S27 H46 Q48 T64 G65 G66 K67 K69

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component