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Structure of PDB 8g5y Chain SK Binding Site BS01

Receptor Information >8g5y Chain SK (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQ SLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRR

Ligand information >8g5y Chain S2 (length=1680) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg cgggggggaugcgugcauuuaucaguggugacucuagauaaccucgggcc gaucgcacgccccccguggcggcgacgacccauucgaacgucugcccuau caacuuucgaugguagucgccgugccuaccauggugaccacgggugacgg ggaaucaggguucgauuccggagagggagccugagaaacggcuaccacau ccaaggaaggcagcaggcgcgcaaauuacccacucccgacccggggaggu agugacgaaaaauaacaauacaggacucuuucgaggcccuguaauuggaa ugaguccacuuuaaauccuuuaacgaggauccauuggagggcaagucugg ugccagcagccgcgguaauuccagcuccaauagcguauauuaaaguugcu gcaguuaaaaagcucguaguuggaucuuuuuacuuugaaaaaauuagagu guucaaagcaggcccgagccgccuggauaccgcagcuaggaauaauggaa uaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauuaa gagggacggccgggggcauucguauugcgccgcuagaggugaaauucuug gaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuuca uuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucgua guuccgaccauaaacgaugccgaccggcgaugcggcggcguuauucccau gacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggggga guaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccacca ggaguggagccugcggcuuaauuugacucaacacgggaaaccucacccgg cccggacacggacaggauugacagauugauagcucuuucucgauuccgug ggugguggugcauggccguucuuaguugguggagcgauuugucugguuaa uuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccccg agcggucggcgucccccaacuucuuagagggacaaguggcguucagccac ccgagauugagcaauaacaggucugugaugcccuuagauguccggggcug cacgcgcgcuacacugacuggcucagcgugugccuacccuacgccggcag gcgcggguaacccguugaaccccauucgugauggggaucggggauugcaa uuauuccccaugaacgaggaauucccaguaagugcgggucauaagcuugc guugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccgau uggaugguuuagugaggcccucggaucggccccgccggcggagcgcugag aagacggucgaacuugacuaucuagaggaaguaaaagucguaacaagguu uccguaggugaaccugcggaaggaucauua ...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<. <<<..<<....<<....<<..........>>...>>.>>......<<... .....<<<.<....<<....<<<<<..................<<..... <<.<<<.....>>>.>>......>>.........<<<<...<<<<<.... ..>>>>>...>>>><<..<<<<<...<......>..>>>>>......>>. ..<<<<.<<<<......>>>>>>>>.>>.>>>...>>..>.>>>.<<<.. ..<<<....<<<<<<<.........>>>>>>>>>>......>>>...<<< .<<<<....>>>>....>>>.>>.<<.<<<..........>>>.>>.<.< <....>>.>...>>>>>>.........<<<....<<<<...>>>>..>>> ..>...>>.>.....<<<<<<<<<.<<<....>>.>.>>>>>.>>>>... ...<<..<...........>..>>.........<<<<<((......<<<< .....<<..))>>.......>>>>.>>>>>..>>>>>>.>>>........ .<.<((.....<.<<...<<<.<<.....<<<<<<.<.......<<...< .......>.<<<<.......>>>>...>>......>.>>>..>>>..... ...<.<<.<<<<<<<...............>>>>>>>.>>.>....>>.. ..<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>... ...>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>>>. ..>>>...>>.>....<<<<<<<...<...<<<<.........>>>>... >>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<<....>> >>>>>>>>>.>..>>>...<<..))>>...>>.....>>>.>.>.<<<.. ....<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.. <<<<<..<<<.<<<<<.......<<........>>..........<<<<< .<....<<<<<<.......<<.<<<........>>>.>>.....>>>>>> ...<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<.... ..>>>...>>.>>>....<<<...<...<<<<..<<<<<<<<<<<<.... ...>>>>.>>>>.....>>>>..>>>>..>.....<<<<<.....>>>>> ........>>>....>>>.>>>.....>>>>>>>.....>.>>>>>.... >.>>>>.>>>.....<<.<<<........<.......<<<.<<<<....> >>>.>>>....>.........>>>.>>............<<<<<...... ....>>>>>...........>>>>>.....<<<<<<<<.......>>>>> >>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<... .<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<..>>>>...>>>>>. ..>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....< <<<<<<<<<..>>>>>>>>>>.........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8g5y mRNA decoding in human is kinetically and structurally distinct from bacteria. Resolution 2.29 Å Binding residue (original residue number in PDB) M1 L2 M3 R8 K25 L43 K47 Q50 S51 S54 R55 F62 Binding residue (residue number reindexed from 1) M1 L2 M3 R8 K25 L43 K47 Q50 S51 S54 R55 F62

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0003735 structural constituent of ribosome GO:0005515 protein binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component