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Structure of PDB 8wq4 Chain S10P Binding Site BS01

Receptor Information >8wq4 Chain S10P (length=100) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] TKARIRLWSSNIDSLNFVVNQIRNMAQKTGIQVSGPIPLPTTRMEVPVMR LPHGEGKKKWEHWEMKVHKRIIDIAADERVMRQLMRVRVPDDVYIEIELI

Ligand information >8wq4 Chain A16S (length=1325) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc augggagucuuacacucccggguaagggaguguggcggacggcugaguaa cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu auagguauuucccguuuguagccgcccgaggauggggcuacggcccauca ggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccgu ggaagcgggagccuccaguugggcacugagacaagggcccaggcccuacg gggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgcu accccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcggggg aauaagcggggggcaagucuggugucagccgccgcgguaauaccagcucc gcgaguggucggggugauuacugggccuaaagcgccuguagccggcccac caagucgccccuuaaaguccccggcucaaccggggaacugggggcgauac uggugggcuagggggcgggagaggcgggggguacucccggaguaggggcg aaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuaga acgcgcccgacggugagaggcgaaagccgggggucccggcuguaaacgau gcgggcuaggugucgaguaggcuuagagccuacucggugccgcagggaag ccguuaagcccgccgccuggggaguacggucgcaagacugaaacuuaaag gaauuggcgggggagcaccacaagggguggaaccugcggcucaauuggag ucaacgccuggaaucuuaccggggagaccgcaguaugacggccaggcuaa cgaccuugccugacucgcggagaggaggugcauggccgucgccagcucgu guugugaaauguccgguuaaguccggcaacgagcgagacccccaccccua guugguauucuggacuccgguccagaaccacacuagggggacugccggcg uaagccggaggaaggagggggccacggcaggucagcaugccccgaaaccg ggccgcacgcggguuacaauggcagggacaacgggaugcuaccucgaaag ggggagccaauccuuaaacccugccgcaguugggaucgagggcugaaacc cgcccucgugaacgaggaaucccuaguaaccgcgggucaacaacccgcgg ugaauacgucccugcuccuugcaca ...<<<<<...((((>>>>>.<<<<<<<<......<<<.<<......<<< .<<<...<...<.<<<<<........>>>>>.>.>.......<<..<... ..<<<<<<<..<<...<<<<<<<.<<<<<....<<<<........>>>>. ....>>>>>....<<.<<<.<<<.......>>>>>.>>.>......<<<< <<.<...........>.>>>>>>.>>>>>>>..>>>>>>>>>.<<<.... <<....<<<<<<<.......>>>>>>>..>>......>>>....<<<<<< ....>>>>...>>..>>>.<<<<<............>>>>>.<<<<<..> >>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>> ..>>>....<<<<<.....>>>>>...<<<<<<<.........>>>>>>> .....<<<<<((......<<<<.....<<..))>>.......>>>>.>>> >>...>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<< <.<<..<<<<<......<<<<<<<.....>>>>>>>....>>>>>....> >>>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<....<<.... ....>>.......>>>>>>>..>>.......<<....>>.>>>>>>>... .>>>.>>>...>>>...>>>>....<<<<<.....>>>>>.......... <<<<<<..<<<.<<<<<<<<<<.....>>>>>>>>>>.>>>...<<..)) >>.....>>>>>>.>>>..<<.....<<<<<....>>>>>...>>...)) ))..........<<<<<..<<.<<<<<...<<<<<<<.<<......<... .......>..........<<<..........<........<<.<<<.... ...>>>.>>.....>........<<.<<....<<<<<<<.....<<<<<. <<......>>..<<<<......>>>>...>>>>>....<<<<<.<<<<.< <.........<<<<<....>>>>>........>>.>>>>.....<<<<<. ...>>>>>........>>>>>.....>>.>>>...>>..>>>>.....>> >...>>..>>>>>>>.....<<<<<<<......<<..<<..<<<...... >>>..>>....>>.....>>>>>>>.............<<<<<....... .>>>>>.............>>>>>....<<<<<<<<.......>>>>>>> >......>>...>>>>>........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wq4 Structural basis of translation inhibition by a valine tRNA-derived fragment Resolution 4.53 Å Binding residue (original residue number in PDB) G37 P38 I39 P40 L41 P42 T44 R45 E47 R52 L53 H55 G56 E57 G58 K59 K61 W62 R72 I73 D75 Binding residue (residue number reindexed from 1) G35 P36 I37 P38 L39 P40 T42 R43 E45 R50 L51 H53 G54 E55 G56 K57 K59 W60 R70 I71 D73

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0000049 tRNA binding GO:0003723 RNA binding GO:0003735 structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

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View graph for Cellular Component