Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP

Structure of PDB 8ree Chain M Binding Site BS01

Receptor Information
>8ree Chain M (length=329) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGTPSGNGVGETTQSLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYL
TIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLS
QFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQ
SLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSDSLPSANDTLLRV
SRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSP
RGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLT
SMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8ree Chain N (length=45) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctggcacgacttttgcactcgatcgaatgctgttgcacattcat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ree Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		L367 S382 R383 K400 S405 S438 D439 P469
Binding residue
(residue number reindexed from 1)		L224 S239 R240 K257 S262 S295 D296 P326
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8ree, PDBe:8ree, PDBj:8ree
PDBsum8ree
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

[Back to BioLiP]

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417