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BioLiP

Structure of PDB 2vus Chain J Binding Site BS01

Receptor Information
>2vus Chain J (length=42) Species: 227321 (Aspergillus nidulans FGSC A4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTCTNCFTQTTPLWRRNPEGQPLCNACGLFLKLHGVVRPLSL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2vus Chain J Residue 1713 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vus Structural Analysis of the Recognition of the Negative Regulator Nmra and DNA by the Zinc Finger from the Gata-Type Transcription Factor Area.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		C673 C676 C694 C697
Binding residue
(residue number reindexed from 1)		C3 C6 C24 C27
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:2vus, PDBe:2vus, PDBj:2vus
PDBsum2vus
PubMed18602114
UniProtP17429|AREA_EMENI Nitrogen regulatory protein areA (Gene Name=areA)

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