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Structure of PDB 4xvu Chain H Binding Site BS01

Receptor Information >4xvu Chain H (length=311) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] TVEPNLHSLITSTTHKWIFVGGKGGVGKTTSSCSIAIQMALSQPNKQFLL ISTNPAHNLSDAFGEKFGKDARKVTGMNNLSCMEIDPSAALKDMNDMGAL ADLTGSIPGIDEALSFMEVMKHIKRQEQGETFDTVIFDTAPTGHTLRFLQ LPNTLSKLLEKFGEITNKLGISGKLNELKANVETIRQQFTDPDLTTFVCV CISEFLSLYETERLIQELISYDMDVNSIIVNQLLFAENDQEHNCKRCQAR WKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLNNLTKFSQFLNKEYNPI TDGKVIYELED

Ligand information >4xvu Chain g (length=12) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] AAAAAAAAAAAA

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 4xvu Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Resolution 2.35 Å Binding residue (original residue number in PDB) M97 M143 Binding residue (residue number reindexed from 1) M94 M117

Enzymatic activity Catalytic site (original residue number in PDB) G28 G30 K31 T32 T33 N57 Catalytic site (residue number reindexed from 1) G25 G27 K28 T29 T30 N54 Enzyme Commision number 3.6.-.-

Gene Ontology Molecular Function GO:0005085 guanyl-nucleotide exchange factor activity GO:0005515 protein binding GO:0005524 ATP binding GO:0008270 zinc ion binding GO:0016787 hydrolase activity GO:0016887 ATP hydrolysis activity GO:0042802 identical protein binding GO:0044183 protein folding chaperone GO:0046872 metal ion binding GO:0051082 unfolded protein binding

	Biological Process
GO:0000750	pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0006457	protein folding
GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0009408	response to heat
GO:0010038	response to metal ion
GO:0016192	vesicle-mediated transport
GO:0034599	cellular response to oxidative stress
GO:0045048	protein insertion into ER membrane
GO:0046685	response to arsenic-containing substance
GO:0071816	tail-anchored membrane protein insertion into ER membrane

	Cellular Component
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0043529	GET complex

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