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BioLiP

Structure of PDB 4bh6 Chain G Binding Site BS01

Receptor Information
>4bh6 Chain G (length=303) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQIAKVPYRVLDAPSLADDFYYSLIDWSSTDVLAVALGKSIFLTDNNTGD
VVHLCDTENEYTSLSWIGAGSHLAVGQANGLVEIYDVMKRKCIRTLSGHI
DRVACLSWNNHVLTSGSRDHRILHRDVRMPDPFFETIESHTQEVCGLKWN
VADNKLASGGNDNVVHVYEGTSKSPILTFDEHKAAVKAMAWSPHKRGVLA
TGGGTADRRLKIWNVNTSIKMSDIDSGSQICNMVWSKNTNELVTSHGYSK
YNLTLWDCNSMDPIAILKGHSFRVLHLTLSNDGTTVVSGAGDETLRYWKL
FDK
Ligand information
>4bh6 Chain O (length=20) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QFMLYEETAEERNIAVHRHN
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bh6 Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		L325 I337 R338 T339 N354 H355 V371 R372
Binding residue
(residue number reindexed from 1)		L81 I93 R94 T95 N110 H111 V127 R128
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0010997 anaphase-promoting complex binding
GO:0097027 ubiquitin-protein transferase activator activity
Biological Process
GO:1904668 positive regulation of ubiquitin protein ligase activity

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Molecular Function
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Biological Process
External links
PDB RCSB:4bh6, PDBe:4bh6, PDBj:4bh6
PDBsum4bh6
PubMed23707760
UniProtP53197|CDH1_YEAST APC/C activator protein CDH1 (Gene Name=CDH1)

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