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BioLiP

Structure of PDB 2zrt Chain G Binding Site BS01

Receptor Information
>2zrt Chain G (length=163) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRE
NKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYR
LSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGW
IQVSYEQYLSMVF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2zrt Chain G Residue 990 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2zrt Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2
Resolution3.3 Å
Binding residue
(original residue number in PDB)		S40 V42 E47
Binding residue
(residue number reindexed from 1)		S15 V17 E22
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) F85 G108 I110
Catalytic site (residue number reindexed from 1) F60 G83 I85
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2zrt, PDBe:2zrt, PDBj:2zrt
PDBsum2zrt
PubMed18997320
UniProtO75340|PDCD6_HUMAN Programmed cell death protein 6 (Gene Name=PDCD6)

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