BioLiP

Structure of PDB 8eaj Chain E Binding Site BS01

Receptor Information

>8eaj Chain E (length=589) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFN
ENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRV
IELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWP
EDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPS
GQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIY
MKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALAL
ALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTG
KGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRV
AIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNIN
LPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRK
YIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEAL
IRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM

Ligand information

>8eaj Chain X (length=11) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

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Receptor-Ligand Complex Structure

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Structure summary

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PDB	8eaj Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation.
Resolution	2.45 Å
Binding residue (original residue number in PDB)	T369 A431
Binding residue (residue number reindexed from 1)	T354 A416

Enzymatic activity

Enzyme Commision number

3.6.4.12: DNA helicase.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0005524	ATP binding
GO:0016887	ATP hydrolysis activity

	Biological Process
GO:0032508	DNA duplex unwinding

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Molecular Function

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Biological Process

PDB	RCSB:8eaj, PDBe:8eaj, PDBj:8eaj
PDBsum	8eaj
PubMed	36499022
UniProt	Q9UXG1\|MCM_SACS2 Minichromosome maintenance protein MCM (Gene Name=MCM)