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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

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Structure of PDB 8cpl Chain D Binding Site BS01

Receptor Information >8cpl Chain D (length=456) Species: 1280,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] SALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVT AGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQ NQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAAL KLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFR HVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVR KLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMP IGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQ AEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEM FRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEQ QNAFYE

Ligand information Ligand ID PLP InChI InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14) InChIKey NGVDGCNFYWLIFO-UHFFFAOYSA-N SMILES Software SMILES CACTVS 3.341 Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O OpenEye OEToolkits 1.5.0 Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O ACDLabs 10.04 O=P(O)(O)OCc1cnc(c(O)c1C=O)C Formula C8 H10 N O6 P Name PYRIDOXAL-5'-PHOSPHATE; VITAMIN B6 Phosphate ChEMBL CHEMBL82202 DrugBank DB00114 ZINC ZINC000001532514 PDB chain 8cpl Chain D Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8cpl Engineered imaging scaffolds for cryo-EM of small proteins of interest. Resolution 1.605 Å Binding residue (original residue number in PDB) S149 G150 T151 F180 H181 G182 E238 D271 V273 Q274 K300 Binding residue (residue number reindexed from 1) S141 G142 T143 F172 H173 G174 E230 D263 V265 Q266 K292 Annotation score 1

Enzymatic activity Enzyme Commision number 2.6.1.29: diamine transaminase. 2.6.1.82: putrescine--2-oxoglutarate transaminase.

Gene Ontology Molecular Function GO:0008483 transaminase activity GO:0019161 diamine transaminase activity GO:0030170 pyridoxal phosphate binding GO:0033094 putrescine--2-oxoglutarate transaminase activity GO:0042802 identical protein binding GO:0042803 protein homodimerization activity

	Biological Process
GO:0009447	putrescine catabolic process
GO:0019477	L-lysine catabolic process

	Cellular Component
GO:0005829	cytosol

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