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BioLiP

Structure of PDB 1i7a Chain D Binding Site BS01

Receptor Information
>1i7a Chain D (length=103) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQPIFTTRAHVFQINWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIIN
STITPNMTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVRE
AAR
Ligand information
Ligand IDPHE
InChIInChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
InChIKeyCOLNVLDHVKWLRT-QMMMGPOBSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](Cc1ccccc1)C(O)=O
CACTVS 3.341N[C@@H](Cc1ccccc1)C(O)=O
OpenEye OEToolkits 1.5.0c1ccc(cc1)CC(C(=O)O)N
OpenEye OEToolkits 1.5.0c1ccc(cc1)C[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)Cc1ccccc1
FormulaC9 H11 N O2
NamePHENYLALANINE
ChEMBLCHEMBL301523
DrugBankDB00120
ZINCZINC000000105196
PDB chain1i7a Chain D Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1i7a The N-terminal domain of Homer/Vesl is a new class II EVH1 domain.
Resolution2.24 Å
Binding residue
(original residue number in PDB)		W24 T70 F74
Binding residue
(residue number reindexed from 1)		W16 T62 F66
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0035256 G protein-coupled glutamate receptor binding
Biological Process
GO:0007216 G protein-coupled glutamate receptor signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:1i7a, PDBe:1i7a, PDBj:1i7a
PDBsum1i7a
PubMed11491285
UniProtQ9QWW1|HOME2_MOUSE Homer protein homolog 2 (Gene Name=Homer2)

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