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BioLiP

Structure of PDB 6cil Chain C Binding Site BS01

Receptor Information
>6cil Chain C (length=589) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARRQAD
ELEAIGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHAL
RNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTI
AKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMG
DVSEKEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLAD
ESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKL
VREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWR
SNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLE
IGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQE
TVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSF
NSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGQSGNKLF
RRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cil Cracking the DNA Code for V(D)J Recombination.
Resolution4.15 Å
Binding residue
(original residue number in PDB)		T400 A403 Y485 H501 E607 Q978
Binding residue
(residue number reindexed from 1)		T4 A7 Y82 H98 E204 Q560
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cil, PDBe:6cil, PDBj:6cil
PDBsum6cil
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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