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Structure of PDB 3bvh Chain C Binding Site BS01

Receptor Information >3bvh Chain C (length=293) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] THDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGK DCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGS VDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELE DWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSD KFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQG GTYSKASTPNGYANGIIWATWKTRWYSMKKTTMKIIPFNRLTI

Ligand information >3bvh Chain I (length=4) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] GPRP

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 3bvh Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic. Resolution 2.6 Å Binding residue (original residue number in PDB) F295 D301 F322 Q329 K338 C339 H340 Y363 Binding residue (residue number reindexed from 1) F194 D200 F221 Q228 K237 C238 H239 Y262

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005102 signaling receptor binding

	Biological Process
GO:0007596	blood coagulation
GO:0030168	platelet activation
GO:0051258	protein polymerization

	Cellular Component
GO:0005577	fibrinogen complex

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