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Structure of PDB 7usp Chain B Binding Site BS01

Receptor Information
>7usp Chain B (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI
LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7usp Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		Y204 S205 W206 R207 N208 S209 S249 F250 F252 F256
Binding residue
(residue number reindexed from 1)		Y19 S20 W21 R22 N23 S24 S64 F65 F67 F71
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7usp, PDBe:7usp, PDBj:7usp
PDBsum7usp
PubMed35642311
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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