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Structure of PDB 7azl Chain B Binding Site BS01

Receptor Information >7azl Chain B (length=358) Species: 1444266 (Escherichia coli 2-427-07_S4_C3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] SHMKFTVEREHLLKPLQQVSGPPTLPILGNLLLQVADGTLSLTGTDLEME MVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVR YYLNGMLFETEGEELRTVATDGHRLAVCSMPSLPSHSVIVPRKGVIELMR MLDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEA GCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDV TYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAA YVVMPMRL

Ligand information >7azl Chain G (length=5) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] QFDLF

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7azl Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. Resolution 2.42 Å Binding residue (original residue number in PDB) L155 T172 G174 H175 P242 V247 V344 M362 P363 M364 R365 Binding residue (residue number reindexed from 1) L153 T170 G172 H173 P234 V239 V336 M354 P355 M356 R357

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003887 DNA-directed DNA polymerase activity GO:0005515 protein binding GO:0008408 3'-5' exonuclease activity GO:0042802 identical protein binding GO:0042803 protein homodimerization activity

	Biological Process
GO:0006260	DNA replication
GO:0006261	DNA-templated DNA replication
GO:0006271	DNA strand elongation involved in DNA replication
GO:0006974	DNA damage response
GO:0030174	regulation of DNA-templated DNA replication initiation
GO:0032297	negative regulation of DNA-templated DNA replication initiation
GO:0042276	error-prone translesion synthesis
GO:0044787	bacterial-type DNA replication

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0009360	DNA polymerase III complex
GO:0030894	replisome
GO:1990078	replication inhibiting complex
GO:1990085	Hda-beta clamp complex

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