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BioLiP

Structure of PDB 4xzr Chain B Binding Site BS01

Receptor Information
>4xzr Chain B (length=423) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLV
EFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGS
VEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTAT
WTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSD
GPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQV
VINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIP
PLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDL
LEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKI
FNCQQNENDKIYEKAYKIIETYF
Ligand information
>4xzr Chain A (length=18) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TRKKRKDPDSNSKENKID
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4xzr Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		R117 W153 N157 A159 S160 G161 T166 E191 Q192 W195 N199 D203 W237 K246 G287 V327 T328 W363 S366 N367 A370 E402 W405 N409 S412 R443
Binding residue
(residue number reindexed from 1)		R31 W67 N71 A73 S74 G75 T80 E105 Q106 W109 N113 D117 W151 K160 G201 V241 T242 W277 S280 N281 A284 E316 W319 N323 S326 R357
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4xzr, PDBe:4xzr, PDBj:4xzr
PDBsum4xzr
PubMed26051712
UniProtQ02821|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)

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