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Structure of PDB 4bv0 Chain B Binding Site BS01

Receptor Information
>4bv0 Chain B (length=302) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNGVTLFTLARLQSRVDYYL
GSLALSDLLILLFALPVDVYNFIWVHHPWAFGDAGCKGYYFLREACTYAT
ALNVVSLSVELYLAIRHPFKHKTMSRSRTKKFISAIWLASALLAIPMLFT
VGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQLNTFMSFLFPMLVASILN
TVIARRLTVMVRVQALRRGVLVLRAMVIAFVVCWLPYHVRRLMFVYISDE
QWTTALFDFYHYFYMLSNALVYVSAAINPILYNLVSANFRQVFLSTLACL
CP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4bv0 Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Resolution3.1 Å
Binding residue
(original residue number in PDB)
D54 L55 F128 H132 Y146 V224 T226 P227 R327 F331 I334 S335 D336 W339 F344 Y347
Binding residue
(residue number reindexed from 1)
D4 L5 F72 H76 Y90 V167 T169 P170 R240 F244 I247 S248 D249 W252 F257 Y260
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4bv0, PDBe:4bv0, PDBj:4bv0
PDBsum4bv0
PubMed24453215
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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