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Structure of PDB 2z73 Chain B Binding Site BS01

Receptor Information >2z73 Chain B (length=347) Species: 6637 (Todarodes pacificus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ETWWYNPSIVVHPHWREFDQVPDAVYYSLGIFIGICGIIGCGGNGIVIYL FTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAAC KVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMIIF VWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYISRDSTTRSNILCMFILG FFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELRKAQAGANAEMR LAKISIVIVSQFLLSWSPYAVVALLAQFGPLEWVTPYAAQLPVMFAKASA IHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIP

Ligand information Ligand ID RET InChI InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+ InChIKey NCYCYZXNIZJOKI-OVSJKPMPSA-N SMILES Software SMILES CACTVS 3.370 CC(=C\C=O)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C ACDLabs 12.01 O=C\C=C(\C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)C)C OpenEye OEToolkits 1.7.0 CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C OpenEye OEToolkits 1.7.0 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=O)C)C CACTVS 3.370 CC(=CC=O)C=CC=C(C)C=CC1=C(C)CCCC1(C)C Formula C20 H28 O Name RETINAL ChEMBL CHEMBL81379 DrugBank ZINC ZINC000004228262 PDB chain 2z73 Chain B Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 2z73 Crystal structure of squid rhodopsin. Resolution 2.5 Å Binding residue (original residue number in PDB) N87 G116 F120 F188 F205 F209 W274 K305 Binding residue (residue number reindexed from 1) N79 G108 F112 F180 F197 F201 W266 K297 Annotation score 4

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0004930 G protein-coupled receptor activity GO:0008020 G protein-coupled photoreceptor activity GO:0009881 photoreceptor activity GO:0016918 retinal binding

	Biological Process
GO:0007186	G protein-coupled receptor signaling pathway
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0009584	detection of visible light
GO:0071482	cellular response to light stimulus

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0033583	rhabdomere membrane
GO:0042995	cell projection

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