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Structure of PDB 1vzt Chain B Binding Site BS01

Receptor Information >1vzt Chain B (length=287) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] KLKLSDWFNPFKRPEVVTMTKWKAPVVWEGTYNRAVLDNYYAKQKITVGL TVFAVGRYIEHYLEEFLTSANKHFMVGHPVIFYIMVDDVSRMPLIELGPL RSFKVFKIKPEKRWQDISMMRMKTIGEHIVAHIQHEVDFLFCMDVDQVFQ DKFGVETLGESVAQLQAGWYKADPNDFTYERRKESAAYIPFGEGDFYYHA AIFGGTPTQVLNITQECFKGILKDKKNDIEAQWHDESHLNKYFLLNKPTK ILSPEYCWDYHIGLPADIKLVKMSWQTKEYNVVRNNV

Ligand information Ligand ID MN InChI InChI=1S/Mn/q+2 InChIKey WAEMQWOKJMHJLA-UHFFFAOYSA-N SMILES Software SMILES ACDLabs 10.04 OpenEye OEToolkits 1.5.0 [Mn+2] CACTVS 3.341 [Mn++] Formula Mn Name MANGANESE (II) ION ChEMBL DrugBank DB06757 ZINC PDB chain 1vzt Chain B Residue 2369 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1vzt Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity. Resolution 2.0 Å Binding residue (original residue number in PDB) D1225 D1227 Binding residue (residue number reindexed from 1) D144 D146 Annotation score 1

Enzymatic activity Catalytic site (original residue number in PDB) Q1247 H1280 W1314 E1317 W1356 R1365 Catalytic site (residue number reindexed from 1) Q166 H199 W233 E236 W275 R284 Enzyme Commision number 2.4.1.87: N-acetyllactosaminide 3-alpha-galactosyltransferase.

Gene Ontology Molecular Function GO:0016758 hexosyltransferase activity

	Biological Process
GO:0005975	carbohydrate metabolic process

	Cellular Component
GO:0016020	membrane

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