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BioLiP

Structure of PDB 1u8n Chain B Binding Site BS01

Receptor Information
>1u8n Chain B (length=227) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RITLKESGPPLVKPTQTLTLTCSFSGFSLSDFGVGVGWIRQPPGKALEWL
AIIYSDDDKRYSPSLNTRLTITKDTSKNQVVLVMTRVSPVDTATYFCAHR
RGPTTLFGVPIARGPVNAMDVWGQGITVTISSTSTKGPSVFPLAPGAAAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLQTYTCNVNHKPSNTKVDKRVEPKSC
Ligand information
>1u8n Chain C (length=7) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ELDKFAS
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1u8n Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications
Resolution2.56 Å
Binding residue
(original residue number in PDB)		Y52 D54 D56 R58 R95 P98 R100H V100K
Binding residue
(residue number reindexed from 1)		Y54 D56 D58 R60 R100 P103 R113 V116
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