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Structure of PDB 1ott Chain B Binding Site BS01

Receptor Information >1ott Chain B (length=441) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] RRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGA LVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALE DQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFR LKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKA VFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGP IFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGF NLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVL GTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTD NYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEA

Ligand information Ligand ID CL InChI InChI=1S/ClH/h1H/p-1 InChIKey VEXZGXHMUGYJMC-UHFFFAOYSA-M SMILES Software SMILES ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0 [Cl-] Formula Cl Name CHLORIDE ION ChEMBL DrugBank DB14547 ZINC PDB chain 1ott Chain B Residue 466 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1ott Gating the Selectivity Filter in ClC Chloride Channels Resolution 3.0 Å Binding residue (original residue number in PDB) G146 A148 G355 F357 A358 Binding residue (residue number reindexed from 1) G129 A131 G338 F340 A341 Annotation score 5

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005247 voltage-gated chloride channel activity GO:0015297 antiporter activity GO:0042802 identical protein binding GO:0062158 chloride:proton antiporter activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0006821	chloride transport
GO:0055085	transmembrane transport
GO:1902476	chloride transmembrane transport
GO:1902600	proton transmembrane transport
GO:1990451	cellular stress response to acidic pH

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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