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Structure of PDB 1h5y Chain B Binding Site BS01

Receptor Information >1h5y Chain B (length=253) Species: 13773 (Pyrobaculum aerophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] SHMALRIIPCLDIDGGAKVVVKGVNFQGIREVGDPVEMAVRYEEEGADEI AILDITAAPEGRATFIDSVKRVAEAVSIPVLVGGGVRSLEDATTLFRAGA DKVSVNTAAVRNPQLVALLAREFGSQSTVVAIDAKWNGEYYEVYVKGGRE ATGLDAVKWAKEVEELGAGEILLTSIDRDGTGLGYDVELIRRVADSVRIP VIASGGAGRVEHFYEAAAAGADAVLAASLFHFRVLSIAQVKRYLKERGVE VRI

Ligand information Ligand ID PO4 InChI InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3 InChIKey NBIIXXVUZAFLBC-UHFFFAOYSA-K SMILES Software SMILES CACTVS 3.341 [O-][P]([O-])([O-])=O ACDLabs 10.04 [O-]P([O-])([O-])=O OpenEye OEToolkits 1.5.0 [O-]P(=O)([O-])[O-] Formula O4 P Name PHOSPHATE ION ChEMBL DrugBank DB14523 ZINC PDB chain 1h5y Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1h5y Structure of Hisf, a Histidine Biosynthetic Protein from Pyrobaculum Aerophilum Resolution 2.0 Å Binding residue (original residue number in PDB) G84 G85 N106 T107 Binding residue (residue number reindexed from 1) G84 G85 N106 T107 Annotation score 1

Enzymatic activity Catalytic site (original residue number in PDB) D12 D133 Catalytic site (residue number reindexed from 1) D12 D133 Enzyme Commision number 4.3.2.10: imidazole glycerol-phosphate synthase.

Gene Ontology Molecular Function GO:0000107 imidazoleglycerol-phosphate synthase activity GO:0016829 lyase activity

	Biological Process
GO:0000105	L-histidine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm

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