Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 1a4e Chain B Binding Site BS01

Receptor Information >1a4e Chain B (length=488) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENI PQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGD KGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQK RNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSG HTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFE AIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLG PNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQ DRPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLA YNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKKVAE

Ligand information Ligand ID AZI InChI InChI=1S/N3/c1-3-2/q-1 InChIKey IVRMZWNICZWHMI-UHFFFAOYSA-N SMILES Software SMILES ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0 [N-]=[N+]=[N-] Formula N3 Name AZIDE ION ChEMBL CHEMBL79455 DrugBank ZINC PDB chain 1a4e Chain B Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1a4e Structure of catalase-A from Saccharomyces cerevisiae. Resolution 2.4 Å Binding residue (original residue number in PDB) H70 F148 Binding residue (residue number reindexed from 1) H56 F134 Annotation score 1

Enzymatic activity Catalytic site (original residue number in PDB) H70 N143 A332 Catalytic site (residue number reindexed from 1) H56 N129 A318 Enzyme Commision number 1.11.1.6: catalase.

Gene Ontology Molecular Function GO:0004096 catalase activity GO:0004601 peroxidase activity GO:0005515 protein binding GO:0020037 heme binding GO:0046872 metal ion binding

	Biological Process
GO:0000302	response to reactive oxygen species
GO:0006979	response to oxidative stress
GO:0042542	response to hydrogen peroxide
GO:0042744	hydrogen peroxide catabolic process
GO:0098869	cellular oxidant detoxification

	Cellular Component
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005777	peroxisome
GO:0005782	peroxisomal matrix

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component