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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

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Structure of PDB 9abp Chain A Binding Site BS01

Receptor Information >9abp Chain A (length=305) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] NLKLGFLVKQPEEPWFQTEWKFADKAGKDLGFEVIKIAVPDGEKTLNAID SLAASGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKGKPMD TVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAVMAITANELDTARRR TTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPEVKHWLI VGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGS LLGSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKK GLGGK

Ligand information Ligand ID GLA InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6+/m1/s1 InChIKey WQZGKKKJIJFFOK-PHYPRBDBSA-N SMILES Software SMILES CACTVS 3.341 OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O OpenEye OEToolkits 1.5.0 C(C1C(C(C(C(O1)O)O)O)O)O OpenEye OEToolkits 1.5.0 C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O CACTVS 3.341 OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O ACDLabs 10.04 OC1C(O)C(OC(O)C1O)CO Formula C6 H12 O6 Name alpha-D-galactopyranose; alpha-D-galactose; D-galactose; galactose; ALPHA D-GALACTOSE ChEMBL CHEMBL1233058 DrugBank ZINC ZINC000000901155 PDB chain 9abp Chain A Residue 307 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 9abp A Pro to Gly mutation in the hinge of the arabinose-binding protein enhances binding and alters specificity. Sugar-binding and crystallographic studies. Resolution 1.97 Å Binding residue (original residue number in PDB) K10 E14 W16 D89 D90 R151 M204 N205 N232 Binding residue (residue number reindexed from 1) K9 E13 W15 D88 D89 R150 M203 N204 N231 Annotation score 4 Binding affinity MOAD: Kd=0.01uM PDBbind-CN: -logKd/Ki=8.00,Kd=0.01uM

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0015407 ABC-type monosaccharide transporter activity GO:0030246 carbohydrate binding GO:0048029 monosaccharide binding

	Biological Process
GO:0042882	L-arabinose transmembrane transport

	Cellular Component
GO:0016020	membrane
GO:0030288	outer membrane-bounded periplasmic space
GO:0042597	periplasmic space
GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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