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BioLiP

Structure of PDB 7a2y Chain A Binding Site BS01

Receptor Information
>7a2y Chain A (length=60) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVTLFVALYDYEARTEDDLSFHKGEKFQIVNNTEGDWWLAHSLTTGETGY
IPSNYVAPVD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7a2y Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 4.0
Resolution0.97 Å
Binding residue
(original residue number in PDB)		Y91 D99 D100 E116 G117 D118 W119 Y132 P134 N136 Y137
Binding residue
(residue number reindexed from 1)		Y9 D17 D18 E34 G35 D36 W37 Y50 P52 N54 Y55
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:7a2y, PDBe:7a2y, PDBj:7a2y
PDBsum7a2y
PubMed
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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