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Structure of PDB 6vf7 Chain A Binding Site BS01

Receptor Information >6vf7 Chain A (length=326) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] WMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVL KALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQT MKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDL STPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLIT HPKEGQEAGLLPRVMCRLQDQGLILYHQFERSFCIFRLPQPGSWKAVRVD LVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKT FFQAASEEDIFRHLGLEYLPPEQRNA

Ligand information >6vf7 Chain T (length=9) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] cggcatacg

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6vf7 DNA Polymerase Mu, 8-oxodGTP:At Ground State Ternary Complex, 50 mM Mn2+ (15 min) Resolution 1.871 Å Binding residue (original residue number in PDB) L177 F385 E386 R387 R442 R445 R449 L456 N457 Binding residue (residue number reindexed from 1) L41 F229 E230 R231 R274 R277 R281 L288 N289

Enzymatic activity Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003887 DNA-directed DNA polymerase activity GO:0016779 nucleotidyltransferase activity GO:0034061 DNA polymerase activity

	Biological Process
GO:0006281	DNA repair

	Cellular Component
GO:0005634	nucleus

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