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Structure of PDB 6s63 Chain A Binding Site BS01

Receptor Information >6s63 Chain A (length=241) Species: 35743 (Halorubrum sodomense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PAGYDLLGDGRPETLWLGIGTLLMLIGTFYFLVRGWGVTDKDAREYYAVT ILVPGIASAAYLSMFFGIGLTEVTVGGEMLDIYYARYADWLFTTPLLLLD LALLAKVDRVTIGTLVGVDALMIVTGLIGALSHTAIARYSWWLFSTICMI VVLYFLATSLRSAAKERGPEVASTFNTLTALVLVLWTAYPILWIIGTEGA GVVGLGIETLLFMVLDVTAKVGFGFILLRSRAILGDTEAPE

Ligand information Ligand ID RET InChI InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+ InChIKey NCYCYZXNIZJOKI-OVSJKPMPSA-N SMILES Software SMILES CACTVS 3.370 CC(=C\C=O)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C ACDLabs 12.01 O=C\C=C(\C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)C)C OpenEye OEToolkits 1.7.0 CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C=O)/C)/C OpenEye OEToolkits 1.7.0 CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=O)C)C CACTVS 3.370 CC(=CC=O)C=CC=C(C)C=CC1=C(C)CCCC1(C)C Formula C20 H28 O Name RETINAL ChEMBL CHEMBL81379 DrugBank ZINC ZINC000004228262 PDB chain 6s63 Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6s63 Two states of a light-sensitive membrane protein captured at room temperature using thin-film sample mounts. Resolution 1.85 Å Binding residue (original residue number in PDB) W96 T100 S151 W192 Y195 P196 W199 K226 Binding residue (residue number reindexed from 1) W90 T94 S145 W186 Y189 P190 W193 K220 Annotation score 4

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005216 monoatomic ion channel activity GO:0009881 photoreceptor activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0007602	phototransduction
GO:1902600	proton transmembrane transport

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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