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Structure of PDB 6kzg Chain A Binding Site BS01

Receptor Information >6kzg Chain A (length=228) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] QGEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYK NVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLE LLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAY QEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEA IAELDTLSYKDSTLIMQLLRDNLTLWTS

Ligand information >6kzg Chain C (length=8) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] RSMSETGT

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6kzg 14-3-3 protein in Complex with CIC S301 phosphorylated peptide Resolution 2.0 Å Binding residue (original residue number in PDB) K49 R56 R127 Y128 L172 N173 L220 D223 N224 L227 Binding residue (residue number reindexed from 1) K50 R57 R128 Y129 L173 N174 L218 D221 N222 L225

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005515 protein binding GO:0019904 protein domain specific binding GO:0042802 identical protein binding GO:0044325 transmembrane transporter binding GO:0071889 14-3-3 protein binding

	Biological Process
GO:0006605	protein targeting
GO:0007165	signal transduction
GO:0007264	small GTPase-mediated signal transduction
GO:0008104	protein localization
GO:0021762	substantia nigra development
GO:0034766	negative regulation of monoatomic ion transmembrane transport
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0016020	membrane
GO:0032991	protein-containing complex
GO:0045202	synapse
GO:0070062	extracellular exosome

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