BioLiP

Structure of PDB 6j31 Chain A Binding Site BS01

Receptor Information

>6j31 Chain A (length=385) Species: 2063 (Kitasatospora) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PRPGHIAMVSVPSRGHLHPSLELIRELVARGHRVTYANDPSVAAAVTETG
AELVPYTSALPTDQIAQMDVFLDDAVGMLPQLRAAYEEDRPDVFLYDVLA
YPARVLAMNWGIPSIQISPTWVMPEKYRERMAPVVEQLKQDPRGAAHYRR
FDAWLEDSGVPGIDAGDLVNLPERSLVLVPRFLQPDADDVDEKRFTFIGP
CLGRRAHQGDWKRPAGAEKVALVSLGSHLTNQLPFYETCVEVFAALPDWH
LVLQIGRHVDAGELGELPPNVEVHNWVPQLAVLEQADVFVTHGGMGGIQE
GLFSGVPMVVAPQANDQPANAESVVGLGIARRIDIATVTPDRLRAAVVEL
ASDPAVAERLSGLRRELRAHGGTMRAADLIERQLP

Ligand information

>6j31 Chain E (length=9) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PNVFVGGVL

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6j31 Genome mining and biosynthesis of kitacinnamycins as a STING activator.
Resolution	2.244 Å
Binding residue (original residue number in PDB)	Q77 M78 F81 W131 M133 Y137 M141 Y158 A175 G176 V179 N180 N325
Binding residue (residue number reindexed from 1)	Q67 M68 F71 W121 M123 Y127 M131 Y148 A165 G166 V169 N170 N315

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0008194	UDP-glycosyltransferase activity
GO:0016740	transferase activity
GO:0016758	hexosyltransferase activity

	Biological Process
GO:0017000	antibiotic biosynthetic process

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Molecular Function

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Biological Process

PDB	RCSB:6j31, PDBe:6j31, PDBj:6j31
PDBsum	6j31
PubMed	31160959
UniProt	A0A514S208