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BioLiP

Structure of PDB 6cil Chain A Binding Site BS01

Receptor Information
>6cil Chain A (length=585) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNEHRQADELEAIMQG
RGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAE
KVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRF
RYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSE
KEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSELCCKPLCLMLADESDH
ETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDEKLVREV
EGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEVWRSNPY
HESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEV
YKHPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDA
VCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQR
FAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGQSGNKLFRRFR
KMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cil Cracking the DNA Code for V(D)J Recombination.
Resolution4.15 Å
Binding residue
(original residue number in PDB)		R848 M849 Q962 N965 R969
Binding residue
(residue number reindexed from 1)		R433 M434 Q540 N543 R547
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cil, PDBe:6cil, PDBj:6cil
PDBsum6cil
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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