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Structure of PDB 5d84 Chain A Binding Site BS01

Receptor Information >5d84 Chain A (length=318) Species: 426430 (Staphylococcus aureus subsp. aureus str. Newman) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ACHDSLLDSVGQTPMVQLHQLFPKHEVFAKLEYMNPGGSMKDRPAKYIIE HGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNL KIIKSYGANVEMVEEPDAHGGYLMTRIAKVQELLATIDDAYWINQYANEL NWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMSRKIKEVHPNAQI VAVDAKGSVIFGDKPINRELPGIGASRVPEILNRSEINQVIHVDDYQSAL GCRKLIDYEGIFAGGSTGSIIAAIEQLITSIEEGATIVTILPDRGDRYLD LVYSDTWLEKMKSRQGVK

Ligand information Ligand ID PLP InChI InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14) InChIKey NGVDGCNFYWLIFO-UHFFFAOYSA-N SMILES Software SMILES CACTVS 3.341 Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O OpenEye OEToolkits 1.5.0 Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O ACDLabs 10.04 O=P(O)(O)OCc1cnc(c(O)c1C=O)C Formula C8 H10 N O6 P Name PYRIDOXAL-5'-PHOSPHATE; VITAMIN B6 Phosphate ChEMBL CHEMBL82202 DrugBank DB00114 ZINC ZINC000001532514 PDB chain 5d84 Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 5d84 Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Resolution 1.45 Å Binding residue (original residue number in PDB) K47 N77 V184 S185 T186 T187 S189 G228 S272 P298 D299 Binding residue (residue number reindexed from 1) K41 N71 V178 S179 T180 T181 S183 G222 S266 P292 D293 Annotation score 1

Enzymatic activity Catalytic site (original residue number in PDB) K47 S272 Catalytic site (residue number reindexed from 1) K41 S266 Enzyme Commision number 2.5.1.140: N-(2-amino-2-carboxyethyl)-L-glutamate synthase.

Gene Ontology Molecular Function GO:0004124 cysteine synthase activity GO:0016740 transferase activity GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

	Biological Process
GO:0006535	cysteine biosynthetic process from serine
GO:0019344	cysteine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm

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