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BioLiP

Structure of PDB 4pd1 Chain A Binding Site BS01

Receptor Information
>4pd1 Chain A (length=404) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPA
SVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCG
ADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECV
LAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPG
KIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIIT
SGGDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG
NPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRC
ILTWHHQEPLPWAQSTSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVM
VIGL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pd1 Modulation of gephyrin-glycine receptor affinity by multivalency.
Resolution1.975 Å
Binding residue
(original residue number in PDB)		M326 D327 F330 R653 Y673 M711 P713 Y719 L722 E726 V727 D729
Binding residue
(residue number reindexed from 1)		M6 D7 F10 R327 Y347 M380 P382 Y388 L391 E395 V396 D398
Enzymatic activity
Enzyme Commision number 2.10.1.1: molybdopterin molybdotransferase.
2.7.7.75: molybdopterin adenylyltransferase.
Gene Ontology
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0032324 molybdopterin cofactor biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:4pd1, PDBe:4pd1, PDBj:4pd1
PDBsum4pd1
PubMed25137389
UniProtQ03555|GEPH_RAT Gephyrin (Gene Name=Gphn)

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