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BioLiP

Structure of PDB 4mg2 Chain A Binding Site BS01

Receptor Information
>4mg2 Chain A (length=195) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVAGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELASPIASVSFGASRDFVFRHKDSVAVV
RLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4mg2 The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R98 C169 R198 R241 K242
Binding residue
(residue number reindexed from 1)		R44 C115 R142 R177 K178
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:4mg2, PDBe:4mg2, PDBj:4mg2
PDBsum4mg2
PubMed
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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