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BioLiP

Structure of PDB 3ecb Chain A Binding Site BS01

Receptor Information
>3ecb Chain A (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARW
IEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGC
DVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAG
AAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTL
RCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPL
GKEQKYTCHVEHEGLPEPLTLRW
Ligand information
>3ecb Chain P (length=10) Species: 11704 (Human immunodeficiency virus type 1 (MFA ISOLATE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RGPGRAFVTI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ecb Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position
Resolution1.698 Å
Binding residue
(original residue number in PDB)		Y7 E63 R66 N70 F74 D77 Y84 W114 T143 K146 W147 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)		Y6 E62 R65 N69 F73 D76 Y83 W113 T142 K145 W146 Y158 E162 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3ecb, PDBe:3ecb, PDBj:3ecb
PDBsum3ecb
PubMed19625641
UniProtP01900|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)

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