Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 2nq9 Chain A Binding Site BS01

Receptor Information >2nq9 Chain A (length=279) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTID EFKAACEKYHYTSAQILPHDSALINLGHPVTEALEKSRDAFIDEMQRCEQ LGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQ GSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTF ADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQD DRFDGIPLILETINPDIWAEEIAWLKAQQ

Ligand information >2nq9 Chain B (length=6) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] atatct

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 2nq9 DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Resolution 1.45 Å Binding residue (original residue number in PDB) D229 R230 H231 Binding residue (residue number reindexed from 1) D229 R230 H231 Binding affinity PDBbind-CN: Kd=97nM

Enzymatic activity Enzyme Commision number 3.1.21.2: deoxyribonuclease IV.

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity GO:0004519 endonuclease activity GO:0008081 phosphoric diester hydrolase activity GO:0008270 zinc ion binding GO:0008296 3'-5'-DNA exonuclease activity GO:0008833 deoxyribonuclease IV (phage-T4-induced) activity GO:0016791 phosphatase activity GO:0046872 metal ion binding

	Biological Process
GO:0006281	DNA repair
GO:0006284	base-excision repair

	Cellular Component
GO:0005829	cytosol

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component