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BioLiP

Structure of PDB 2i32 Chain A Binding Site BS01

Receptor Information
>2i32 Chain A (length=154) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAES
EEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCT
YRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFH
INWE
Ligand information
>2i32 Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LKKQVETRTADGRRRITPLCI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2i32 Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		D37 E39 V60 L61 V62 G63 P64 R69 H70 M71 F72 V73 Q75
Binding residue
(residue number reindexed from 1)		D37 E39 V60 L61 V62 G63 P64 R69 H70 M71 F72 V73 Q75
Enzymatic activity
Catalytic site (original residue number in PDB) I107 E116 V146
Catalytic site (residue number reindexed from 1) I107 E116 V146
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006325 chromatin organization
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:2i32, PDBe:2i32, PDBj:2i32
PDBsum2i32
PubMed16980972
UniProtQ9Y294|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)

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