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Structure of PDB 1s4p Chain A Binding Site BS01

Receptor Information >1s4p Chain A (length=335) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] KTTMDYITPSFGKPKACYVTLVRNKELKGLLSSIKYVENKINKKFPYPWV FLNDEPFTEEFKEAVTKAVSSEVKFGILPKEHWSYPEWINQTKAAEIRAD AATKYIYGGSESYRHMCRYQSGFFWRHELLEEYDWYWRVEPDIKLYCDIN YDVFKWMQENEKVYGFTVSIHEYEVTIPTLWQTSMDFIKKNPEYLDENNL MSFLSNDNGKTYNLCHFWSNFEIANLNLWRSPAYREYFDTLDHQGGFFYE RWGDAPVHSIAAALFLPKDKIHYFSDIGYHHPPYDNCPLDKEVYNSNNCE CDQGNDFTFQGYSCGKEYYDAQGLVKPKNWKKFRE

Ligand information Ligand ID MMA InChI InChI=1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1 InChIKey HOVAGTYPODGVJG-VEIUFWFVSA-N SMILES Software SMILES CACTVS 3.341 CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O ACDLabs 10.04 OC1C(O)C(O)C(OC1OC)CO OpenEye OEToolkits 1.5.0 CO[C@@H]1[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O CACTVS 3.341 CO[CH]1O[CH](CO)[CH](O)[CH](O)[CH]1O OpenEye OEToolkits 1.5.0 COC1C(C(C(C(O1)CO)O)O)O Formula C7 H14 O6 Name methyl alpha-D-mannopyranoside; O1-METHYL-MANNOSE; methyl alpha-D-mannoside; methyl D-mannoside; methyl mannoside ChEMBL CHEMBL195368 DrugBank DB01979 ZINC ZINC000004261920 PDB chain 1s4p Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1s4p Structure of Kre2p/Mnt1p: A YEAST {alpha}1,2-MANNOSYLTRANSFERASE INVOLVED IN MANNOPROTEIN BIOSYNTHESIS Resolution 2.01 Å Binding residue (original residue number in PDB) Y220 E279 H323 W325 R358 Binding residue (residue number reindexed from 1) Y113 E172 H216 W218 R251 Annotation score 4

Enzymatic activity Enzyme Commision number 2.4.1.-

Gene Ontology Molecular Function GO:0000030 mannosyltransferase activity

	Biological Process
GO:0006486	protein glycosylation

	Cellular Component
GO:0016020	membrane

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