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Structure of PDB 1gji Chain A Binding Site BS01

Receptor Information >1gji Chain A (length=275) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PYIEIFEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNKTFPSIQILNYFG KVKIRTTLVTKNEPYKPHPHDLVGKDCRDGYYEAEFGPERRVLSFQNLGI QCVKKKDLKESISLRISKKINPFNVPEEQLHNIDEYDLNVVRLCFQAFLP DEHGNYTLALPPLISNPIYDNRAPNTAELRICRVNKNCGSVKGGDEIFIL CDKVQKDDIEVRFVLDNWEAKGSFSQADVHRQVAIVFRTPPFLRDITEPI TVKMQLRRPSDQEVSEPMDFRYLPD

Ligand information >1gji Chain C (length=20) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] gggtttaaagaaattccaga

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1gji X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2. Resolution 2.85 Å Binding residue (original residue number in PDB) Y24 C26 K110 K111 R178 P180 Q211 K212 Q238 Binding residue (residue number reindexed from 1) Y18 C20 K104 K105 R172 P174 Q205 K206 Q232 Binding affinity PDBbind-CN: Kd=25nM

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005737	cytoplasm

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