Structure of PDB 7pjy Chain x

Receptor sequence

>7pjyx (length=697) Species: 83333 (Escherichia coli K-12)

ARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVMDWMEQEQ
ERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLD
GAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQ
IKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDI
PADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVL
NNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPA
ERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAAR
ERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILE
RMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTI
IAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAK
QSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGI
QEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKK
AKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAE
VPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK

3D structure

• PDB: 7pjy Structural mechanism of GTPase-powered ribosome-tRNA movement.
• Chain: x
• Resolution: 3.1 Å

Enzymatic activity

• Enzyme Commision number: 3.6.5.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	x	H17 I18 H91 P120 R145 K506 R511 G632 S635 R636 G643 T667 R670 S671 K674	H17 I18 H85 P114 R139 K500 R505 G626 S629 R630 G637 T661 R664 S665 K668
BS02	rna	x	F328 R356 R358 R361 R436 K540 G541	F322 R350 R352 R355 R430 K534 G535
BS03	rna	x	Q507 S508 G509 H583 V585 D586	Q501 S502 G503 H577 V579 D580
BS04	rna	x	G510 R511	G504 R505
BS05	GDP	x	D19 A20 G21 K22 T23 T24 N141 K142 D144 R145 S267 F269	D19 A20 G21 K22 T23 T24 N135 K136 D138 R139 S261 F263

Gene Ontology

Molecular Function

• GO:0003746 translation elongation factor activity
• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0016787 hydrolase activity
• GO:0097216 guanosine tetraphosphate binding

Biological Process

• GO:0006412 translation
• GO:0006414 translational elongation
• GO:0032790 ribosome disassembly

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:7pjy, PDBe:7pjy, PDBj:7pjy
• PDBsum: 7pjy
• PubMed: 34635670
• UniProt: P0A6M8|EFG_ECOLI Elongation factor G (Gene Name=fusA)