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Structure of PDB 4dx9 Chain u

Receptor sequence

>4dx9u (length=106) Species: 9606 (Homo sapiens)

CAEFRIKYVGAIINYIDVAQQDGKLPFVPPEEEFIMGVSKYGIKVLHRHA
LYLIIRMVCYDDGLGAGKSLLALKTTDASNEEYSLWVYQCNSLEQAQAIC
KVLSTA

3D structure

• PDB: 4dx9 Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation.
• Chain: u
• Resolution: 2.99 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	u	R140 M141 C143 C184	R56 M57 C59 C100

External links

• PDB: RCSB:4dx9, PDBe:4dx9, PDBj:4dx9
• PDBsum: 4dx9
• PubMed: 23317506
• UniProt: O14713|ITBP1_HUMAN Integrin beta-1-binding protein 1 (Gene Name=ITGB1BP1)

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