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BioLiP

Structure of PDB 7tos Chain S15

Receptor sequence
>7tosS15 (length=88) Species: 562 (Escherichia coli) [Search protein sequence]
SLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHH
SRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
3D structure
PDB7tos Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
ChainS15
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna S15 S1 N19 D20 T21 G22 S23 Q27 L30 Q34 H37 H41 H45 K47 D48 H49 H50 S51 R53 G54 R57 S60 K64 Y68 R71 S1 N19 D20 T21 G22 S23 Q27 L30 Q34 H37 H41 H45 K47 D48 H49 H50 S51 R53 G54 R57 S60 K64 Y68 R71
BS02 rna S15 Q39 L55 V59 R62 R88 Q39 L55 V59 R62 R88
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7tos, PDBe:7tos, PDBj:7tos
PDBsum7tos
PubMed35589706
UniProtP0ADZ4|RS15_ECOLI Small ribosomal subunit protein uS15 (Gene Name=rpsO)

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