Structure of PDB 7t2b Chain Q

Receptor sequence
>7t2bQ (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
ASRATPENYLFQGRQECYAFNGTQRFLERYIYNREEFARFDSDVGEFRAV
TELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVN
VSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRN
GDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWK
3D structure
PDB7t2b CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
ChainQ
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide Q G11 R12 Q13 E28 Y30 W61 K71 V74 R77 M78 H81 N82 L85 G13 R14 Q15 E28 Y30 W61 K71 V74 R77 M78 H81 N82 L85
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7t2b, PDBe:7t2b, PDBj:7t2b
PDBsum7t2b
PubMed37100059
UniProtP04440|DPB1_HUMAN HLA class II histocompatibility antigen, DP beta 1 chain (Gene Name=HLA-DPB1)

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