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Structure of PDB 8ys2 Chain O

Receptor sequence

>8ys2O (length=79) Species: 9606 (Homo sapiens)

KCEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVCNN
GQCVPSRWKCDGDPDCEDGSDESPEQCHM

3D structure

• PDB: 8ys2 The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes.
• Chain: O
• Resolution: 5.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	O	W50 D53 D55 D57 D63 E64	W19 D22 D24 D26 D32 E33
BS02	CA	O	W89 D92 D96 D102 E103	W58 D61 D65 D71 E72

External links

• PDB: RCSB:8ys2, PDBe:8ys2, PDBj:8ys2
• PDBsum: 8ys2
• PubMed: 39127734
• UniProt: P98155|VLDLR_HUMAN Very low-density lipoprotein receptor (Gene Name=VLDLR)

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