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Structure of PDB 8sh5 Chain H

Receptor sequence

>8sh5H (length=225) Species: 10090 (Mus musculus)

EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVAS
ISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQG
YRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPKSC

3D structure

• PDB: 8sh5 Crystal structure of a cap-independent translation enhancer RNA.
• Chain: H
• Resolution: 2.75 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Y34 P56 Y57 S58 S60 Q102 Y104 R105 R106 R110	Y31 P53 Y54 S55 S57 Q99 Y101 R102 R103 R107

External links

• PDB: RCSB:8sh5, PDBe:8sh5, PDBj:8sh5
• PDBsum: 8sh5
• PubMed: 37548413

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