Structure of PDB 7snq Chain H

Receptor sequence
>7snqH (length=209) Species: 11678 (Human immunodeficiency virus type 1 BH10) [Search protein sequence]
PIVQNLQGQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQ
DLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVREPRGSDIAGTTST
LQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEP
FRDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPGAT
LEEMMTACQ
3D structure
PDB7snq Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection.
ChainH
Resolution2.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide H N53 L56 N57 Q67 K70 I73 N74 T107 N53 L56 N57 Q67 K70 I73 N74 T97
BS02 peptide H N183 T186 N173 T176
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:7snq, PDBe:7snq, PDBj:7snq
PDBsum7snq
PubMed36202818
UniProtP03366|POL_HV1B1 Gag-Pol polyprotein (Gene Name=gag-pol)

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