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Structure of PDB 4q9r Chain H

Receptor sequence

>4q9rH (length=223) Species: 10090 (Mus musculus)

EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVAS
ISPYSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARQG
YRRRSGRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPK

3D structure

• PDB: 4q9r A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
• Chain: H
• Resolution: 3.12 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	H	Y34 Y57 S58 S60 Q102 Y104 R105 R110	Y31 Y54 S55 S57 Q99 Y101 R102 R107

External links

• PDB: RCSB:4q9r, PDBe:4q9r, PDBj:4q9r
• PDBsum: 4q9r
• PubMed: 24952597

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