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BioLiP

Structure of PDB 4hix Chain H

Receptor sequence
>4hixH (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
VQLLESGGGLVQPGGSLRLSCAASGFTFSNYGMSWVRQAPGKGLEWVASI
RSGGGRTYYSDNVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCVRYDH
YSGSSDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDY
FPQPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI
CNVNHKPSNTKVDKKVEPK
3D structure
PDB4hix Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
ChainH
Resolution2.204 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide H G33 S50 R52 Y58 Y95 S100B G32 S49 R51 Y58 Y98 S105
External links
PDB RCSB:4hix, PDBe:4hix, PDBj:4hix
PDBsum4hix
PubMed23416764
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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