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BioLiP

Structure of PDB 1axs Chain H

Receptor sequence
>1axsH (length=221) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQLLESGAELMKPGASVKISCKATGYTFSSFWIEWVKQRPGHGLEWIGE
ILPGSGGTHYNEKFKGKATFTADKSSNTAYMQLSSLTSEDSAVYYCARGH
SYYFYDGDYWGQGTSVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVK
DYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQT
YICNVNHKPSNTKVDKKVEPK
3D structure
PDB1axs The interplay between binding energy and catalysis in the evolution of a catalytic antibody.
ChainH
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HOP H E35 G95 H96 Y1001 D101 W103 E35 G99 H100 Y105 D108 W110 PDBbind-CN: -logKd/Ki=7.77,Kd=17nM
External links
PDB RCSB:1axs, PDBe:1axs, PDBj:1axs
PDBsum1axs
PubMed9305839
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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