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BioLiP

Structure of PDB 8dyq Chain G

Receptor sequence
>8dyqG (length=222) Species: 485 (Neisseria gonorrhoeae) [Search protein sequence]
THWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITETVSGKLPAIKVNY
KPSMVDVENNGHTIQVNYPEGGNTLTVNGRTYTLKQFHFHVPSENQIKGR
TFPMEAHFVHLDENKQPLVLAVLYEAGKTNGRLSSIWNVMPMTAGKVKLN
QPFDASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKF
TRAVGSENNRPVQPLNARVVIE
3D structure
PDB8dyq Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase.
ChainG
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AZM G H92 H111 V113 L176 T177 T178 H88 H107 V109 L172 T173 T174
BS02 ZN G H92 H94 H111 H88 H90 H107
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Cellular Component
GO:0042597 periplasmic space

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Molecular Function
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Cellular Component
External links
PDB RCSB:8dyq, PDBe:8dyq, PDBj:8dyq
PDBsum8dyq
PubMed36655133
UniProtQ50940|CAH_NEIGO Carbonic anhydrase (Gene Name=cah)

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