BioLiP

Structure of PDB 1bcf Chain F

Receptor sequence

>1bcfF (length=158) Species: 562 (Escherichia coli) [Search protein sequence]

MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVEYHESID
EMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKN
LREAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYL
QAQIREEG

3D structure

PDB

1bcf Structure of a unique twofold symmetric haem-binding site.

Chain

Resolution

2.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.16.3.1: ferroxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEM	F	F26 M52 K53	F26 M52 K53
BS02	MN	F	E51 E94 E127 H130	E51 E94 E127 H130
BS03	MN	F	E18 E51 H54 E127	E18 E51 H54 E127

Gene Ontology

	Molecular Function
GO:0004322	ferroxidase activity
GO:0005506	iron ion binding
GO:0005515	protein binding
GO:0008199	ferric iron binding
GO:0015093	ferrous iron transmembrane transporter activity
GO:0016491	oxidoreductase activity
GO:0020037	heme binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding
GO:0140315	iron ion sequestering activity

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion
GO:0034755	iron ion transmembrane transport

	Cellular Component
GO:0005829	cytosol
GO:0016020	membrane

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Molecular Function

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Cellular Component

PDB	RCSB:1bcf, PDBe:1bcf, PDBj:1bcf
PDBsum	1bcf
PubMed	7664064
UniProt	P0ABD3\|BFR_ECOLI Bacterioferritin (Gene Name=bfr)